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The information contained on this page is provided as general health information and is not intended to substitute as medical advice and direction from your physician or health care provider. Please direct any questions related to your health care provider. In an emergency, call 9-1-1 or go to the nearest emergency center.


Buccal smear

Definition

A buccal  (pronounced "buckle") smear is the painless removal of a sample of cells from the inside of your mouth (cheek) for study.

Alternative Names

Sex chromatin test; Buccal swab

How the Test is Performed

The health care provider will gently scrape the inside of the cheek with a small spatula to collect cells for testing. Sometimes, you can do this yourself.

How to Prepare for the Test

Rinse and wash the mouth as instructed.

How the Test will Feel

You will feel a scraping sensation as cells are removed from the cheek.

Why the Test is Performed

This test is done to get cells for chromosome or DNA analysis, most often for genetic testing.

This test may also help establish sexual identity. When the test is used in this way, it's called the sex chromatin test.

Risks

There are no risks with this test.

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Throat anatomyBuccal  smear - illustration

References

Chernecky CC, Berger BJ. Barr body analysis buccal smear for staining sex chromatin mass - diagnostic. In: Chernecky CC, Berger BJ, eds. Laboratory Tests and Diagnostic Procedures. 6th ed. St Louis, MO: Elsevier Saunders; 2013:186-187.