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The information contained on this page is provided as general health information and is not intended to substitute as medical advice and direction from your physician or health care provider. Please direct any questions related to your health care provider. In an emergency, call 9-1-1 or go to the nearest emergency center.


Post-splenectomy syndrome

Definition

Post-splenectomy syndrome can occur after surgery to remove the spleen. It consists of a group of symptoms and signs such as:

Alternative Names

Splenectomy - post-surgery syndrome; Overwhelming post-splenectomy infection; OPSI; Splenectomy - reactive thrombocytosis

Possible Complications

Possible long-term medical problems include:

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Spleen

References

Connell NT, Shurin SB, Schiffman FJ. The spleen and its disorders. In: Hoffman R, Benz EJ Jr, Silberstein LE, Heslop HE, Weitz JI, Anastasi J, eds. Hematology: Basic Principles and Practice. 6th ed. Philadelphia, PA: Elsevier Saunders; 2013:chap 162.

Poulose BK, Holzman MD. The spleen. In: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. Sabiston Textbook of Surgery: The Biological Basis of Modern Surgical Practice. 20th ed. Philadelphia, PA: Elsevier; 2017:chap 56.