Statin Therapy for Patients with Diabetes - Download PDF Version
Adults 40–75 years of age with diabetes, who do or do not have clinical atherosclerotic cardiovascular disease (ASCVD), should be started on a statin for primary and secondary prevention of ASCVD regardless of lipid status.
Medications
One of the following medications must have been dispensed.
Note: The active ingredients are limited to oral formulations only.
Drug Category
Statin medications
· Lovastatin
· Fluvastatin
· Pravastatin
· Simvastatin
· Rosuvastatin
· Atorvastatin
· Pitavastatin
Statin combination products
· Atorvastatin / amlodipine
· Atorvastatin / ezetimibe
· Lovastatin / niacin
· Simvastatin / ezetimibe
· Simvastatin / niacin
· Simvastatin / sitagliptin
Standard exclusion(s)
Timeframe
· Patients in hospice
· End-stage renal disease (ESRD)
· Any time during the measurement year
· Any time during the measurement year or the year prior to the measurement
High-, Moderate-, and Low-Intensity Statin Therapy
High Intensity
Moderate Intensity
Low Intensity
Daily dose lowers LDL-C on average by ≈ ≥50%
Daily dose lowers LDL-C on average by ≈ 30% to <50%
Daily dose lowers LDL-C on average by <30%
Atorvastatin 40-80 mg
Rosuvastatin 20-40 mg
Atorvastatin 10-20 mg
Rosuvastatin 5-10 mg
Simvastatin 20-40 mg
Pravastatin 40-80 mg
Lovastatin 40 mg
Fluvastatin XL 80 mg
Fluvastatin 40 mg bid
Pitavastatin 2-4 mg
Simvastatin 10 mg
Pravastatin 10-20 mg
Lovastatin 20 mg
Fluvastatin 20-40 mg
Pitavastatin 1 mg
References:
** Promote Statin Use in Diabetics **
If you have any questions, please contact Dr. Preston Thomas, Associate Medical Director at 248-484-4980 or Preston.Thomas@McLaren.org