Boris Pasche, M.D., Ph.D., FACP

Specialties

Oncology - Medical

Board Certification

American Board of Internal Medicine - Medical Oncology, Hematology

Language(s) Spoken

English, French, German, Swedish

Locations

Karmanos Cancer Center
4100 John R
Detroit, MI 48201
Get Directions

Phone:1-800-KARMANOS

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Locations

Karmanos Cancer Center

4100 John R
Detroit, MI 48201
Get Directions

Phone:1-800-KARMANOS

Karmanos Cancer Institute at Lawrence and Idell Weisberg Cancer Center

31995 Northwestern Highway
Farmington Hills, MI 48334
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Education

Additional Info

About

Dr. Pasche has served as president and Chief Executive Officer of the Barbara Ann Karmanos Cancer Institute and chair of the Department of Oncology at Wayne State University since 2023. Before joining Karmanos, he served as director of the Wake Forest Baptist Comprehensive Cancer Center (WFBCCC), principal investigator of the NCI CCSG award, and chair of the Department of Cancer Biology from 2014 until 2022. He was the first to identify and characterize TGFBR1*6A, an in-frame deletion within TGFBR1 exon 1, which has emerged as a low penetrance tumor susceptibility allele. Dr. Pasche is the co-inventor and principal developer of a novel medical device delivering amplitude-modulated radiofrequency electromagnetic fields for systemic targeted cancer treatment. The device is FDA-approved for the treatment of patients with advanced hepatocellular carcinoma who fail first- and second-line therapy.

A native of Switzerland, Dr. Pasche earned his doctorate of medicine and doctorate of philosophy from the Karolinska Institute in Stockholm, Sweden, and another doctorate of medicine from the University of Lausanne in Switzerland. Following a postdoctoral fellowship at the Brigham and Women’s Hospital, Harvard Medical School, Dr. Pasche completed an internship and residency in internal medicine at the New York Hospital at Cornell University Medical Center. He also went on to complete a hematology and oncology fellowship at Memorial Sloan-Kettering Cancer Center and a second postdoctoral fellowship at Howard Hughes Medical Institute and Sloan-Kettering Institute for Cancer Research

Research Interests

Treatment of cancer with radiofrequency electromagnetic fields.
Cancer Genetics.
TGF-ß
Ethnic and Racial Disparities in Multiple Myeloma Education, Diagnosis, and Treatments.

Related News

September 08, 2025
Dr. Boris Pasche Named to Becker’s 2025 Academic Medical Center CEOs to Know

Boris Pasche, M.D., Ph.D., FACP , president and CEO of the Barbara Ann Karmanos Cancer Institute in Detroit, has been listed in the Becker’s Hospital Review’s Academic Medical Center CEOs to Know . The 2025 list includes 95 CEOs nationwide who are setting the pace for the nation’s leading academic medical centers and academic health systems by guiding “institutions that serve as hubs for discovery and innovation, overseeing groundbreaking clinical trials, pioneering technologies and novel treatment mode...
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September 08, 2025
Research and Breakthroughs: Community Conversations on Cancer Delivers Collaborative Dialogue with Community on Latest Cancer Treatments

The Barbara Ann Karmanos Cancer Institute’s Office of Community Outreach and Engagement (COE) has continued its Community Conversations on Cancer series in 2025 in partnership with the Detroit Public Library. The program invites members of the public to dialogue about current cancer research and treatment, improved health outcomes, and a deep understanding of a cancer diagnosis. The 2025 series includes six events, each a collaborative, informative discussion introducing the community to a different asp...
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August 19, 2025
2025 ‘Detroit 500’ List Includes Three McLaren Health Care, Karmanos Cancer Institute Top Executives

President and CEO of McLaren Health Care, Philip A. Incarnati, President and CEO of the Barbara Ann Karmanos Cancer Institute, Boris C. Pasche, M.D., Ph.D., FACP, and President of the Karmanos Cancer Hospital and Karmanos Cancer Network, Brian R. Gamble, have been included in this year’s “Detroit 500.” An annual feature from DBusiness Magazine, the “Detroit 500” compiles the 500 most influential business leaders in metro Detroit, spanning over 30 industries. Individuals are selected based on several fac...
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Boris Pasche, M.D., Ph.D., FACP