McLaren Health Care

IRB Electronic Submission

Accessing iRIS

Submit all new studies and subsequent submissions to the MHC IRB via iRIS.

Existing McLaren users, please use your McLaren credentials to log in to iRIS (user ID and password). When you log into iRIS for the first time, there may be a delay before you can fully use iRIS. After you log in for the first time, the System Administrator will have to manually set your role and department.

Technical Support

The iRIS technical support helpdesk can be reached at Please use this email when you have questions regarding any technical issues with your applications. Non-technical iRIS application issue questions should continue to be sent to

When a user contacts the Research Informatics helpdesk reporting an error or technical problem, the staff will make a good-faith effort to understand the issue and provide a resolution. When the helpdesk staff receives an advanced question or is unable to resolve an issue, the question/issue may need to escalate to iMedRIS Support Services.

Training Resources

To view or print detailed descriptions and guided screenshots, please review the PDF quick guides below. For a view of whole-system functionality and beginner navigation, please review the training video.

Quick Guides

7 pg
7 pg
Accessing and Logging into iRIS coming soon icon
Navigating the Study Assistant Workspace (iRIS Home Screen) coming soon icon
Create a New Submission Part I: Department, KSP, Application Type coming soon icon
Create a New Submission Part II: Review Packet, Attachments, Routing coming soon icon
11 pg
Completing Outstanding Tasks & Responding to Stipulations coming soon icon
Modifications, Continuing Reviews, UPIRSO, Violation/Exception, & Final Report Forms coming soon icon
12 pg

On-Demand Training Classes

Group or individual classes are available upon request. Contact the Research Integrity Office via email at

iRIS Learning Labs

Starting August 2023 (Please be advised, the August 2023 Learning Lab has been CANCELLED), the IRB will offer a monthly iRIS learning lab via Zoom.

Learning lab is held the third Wednesday of every month from 12:00-12:45 p.m.

Registration is not required, just click here to join.

Archived Webinars

Frequently Asked Questions